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Pathology Update 2025

008 - An audit of dysplasia in Barrett Oesophagus within the Gold Coast Hospital and Health Service

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Anatomical Pathology

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Abstracts/Presentation Description

Johnranin Brady1, Sooraj Pillai1
1
Gold Coast University Hospital, Pathology Queensland

Barrett oesophagus is a risk-factor for oesophageal adenocarcinoma. Patients with Barrett oesophagus may develop dysplasia, which is a pre-malignant lesion. Barrett oesophagus and Barrett dysplasia is categorised into four categories 1) negative for dysplasia 2) low-grade dysplasia 3) high-grade dysplasia, and 4) indefinite for dysplasia. There is limited Australian-based data on the rates of Barrett oesophagus and dysplasia arising within Barrett oesophagus. We have performed an audit between 1st January 2020 and 31st December 2023 for all pathological reports of Barrett oesophagus reported within the Gold Coast Hospital and Health Service in Queensland, Australia. 1,504 reports were identified within this timeframe to be of histologically confirmed Barrett oesophagus from 1,175 individual patients. 1,028 cases were negative for dysplasia (87.5%), 6 were indefinite for dysplasia (0.5%), 31 were of low-grade dysplasia (2.6%), and 34 were of high-grade dysplasia (2.9%).  Historically, the categories of indefinite for dysplasia and low-grade dysplasia have low interobserver agreement. Many patients with these diagnoses had repeat biopsies within the audit timeframe and the results of follow-up biopsies are presented here.

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Submitting/Presenting Authors

Dr Johnranin Brady - , Dr Sooraj Pillai - Gold Coast University Hospital

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