Abstracts/Presentation Description
Alex Wang1, Anusha Kapoor1
1Department of Anatomical Pathology, Dorevitch Pathology, Victoria, Australia
Malignant transformation of an ovarian mature teratoma into a primary neuroectodermal tumour is exceptionally rare. It typically presents in young patients with early-stage disease. We present the case of a malignant neuroectodermal tumour arising from an ovarian mature cystic teratoma in a young female. Morphological and immunohistochemical features were consistent with a high-grade glioma. The pathogenesis and molecular drivers of the disease process are poorly understood. This presentation aims to highlight the spectrum of malignant tumours of neuroectodermal origin arising from ovarian teratomas, with an emphasis on morphological, immunohistochemical and molecular characteristics.
1Department of Anatomical Pathology, Dorevitch Pathology, Victoria, Australia
Malignant transformation of an ovarian mature teratoma into a primary neuroectodermal tumour is exceptionally rare. It typically presents in young patients with early-stage disease. We present the case of a malignant neuroectodermal tumour arising from an ovarian mature cystic teratoma in a young female. Morphological and immunohistochemical features were consistent with a high-grade glioma. The pathogenesis and molecular drivers of the disease process are poorly understood. This presentation aims to highlight the spectrum of malignant tumours of neuroectodermal origin arising from ovarian teratomas, with an emphasis on morphological, immunohistochemical and molecular characteristics.
Speaker/Presenting Authors
Authors
Submitting/Presenting Authors
Dr Alex Wang - Department of Anatomical Pathology, Dorevitch Pathology (Victoria, Australia) , Dr Anusha Kapoor - Department of Anatomical Pathology, Dorevitch Pathology (Victoria, Australia)