Alya Aljubaili1, Audrey Choi1. 1 Dorevitch Pathology.

Neuroendocrine carcinomas of the duodenal ampulla are rare. ^1-3 Neuroendocrine carcinomas occurring in the ampulla of vater being less than 1% of all gastroenteric neuroendocrine tumours.^1-3

Given the rarity and similarity to other carcinoma subtypes, diagnostic dilemmas are commonplace. Neuroendocrine carcinomas are aggressive, missing the diagnosis can lead to increased mortality. ^1-3

Treatment involves pancreaticoduodenectomy and adjuvant chemotherapy. ^1-3 Prognosis is generally poor, with survival being up to 8-18 months despite a combination of surgical and medical management.^1-3

This poster will present a case of a patient who was diagnosed with a neuroendocrine carcinoma of the ampulla of vater. Techniques, common pitfalls of diagnosis and differential diagnosis will be discussed. A summary of previous case reports will also be reviewed in this poster.