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Abstracts/Presentation Description
Marco Chan1, Rebecca Williams2
1The Canberra Hospital, Canberra Health Services, Australian Capital Territory; 2Forensic and Scientific Services, Townsville University Hospital, Queensland Health
Melioidosis is an infection caused by the bacterium Burkholderia psuedomallei which is endemic in Northern Territory and Far North Queensland in Australia and other Southeast Asian Countries and carries a high mortality rate worldwide.1,2 The infection typically affects older males, especially those with chronic comorbidities and risk factors such as diabetes and heavy alcohol consumption.3 It can present as an acute or chronic infection with the potential to re-activate through life. Clinical manifestations include a spectrum of multi-organ involvement. In this case report, we present a fatal case of melioidosis which was diagnosed in the postmortem setting with atypical features demographically and clinically. Challenges in pre- and post-mortem diagnosis of melioidosis are discussed.
References:
1. Singh M, Mahmood M. Melioidosis: the great mimicker. J Community Hosp Intern Med Perspect. 2017;7(4):245-247. doi:10.1080/20009666.2017.1348875.
1The Canberra Hospital, Canberra Health Services, Australian Capital Territory; 2Forensic and Scientific Services, Townsville University Hospital, Queensland Health
Melioidosis is an infection caused by the bacterium Burkholderia psuedomallei which is endemic in Northern Territory and Far North Queensland in Australia and other Southeast Asian Countries and carries a high mortality rate worldwide.1,2 The infection typically affects older males, especially those with chronic comorbidities and risk factors such as diabetes and heavy alcohol consumption.3 It can present as an acute or chronic infection with the potential to re-activate through life. Clinical manifestations include a spectrum of multi-organ involvement. In this case report, we present a fatal case of melioidosis which was diagnosed in the postmortem setting with atypical features demographically and clinically. Challenges in pre- and post-mortem diagnosis of melioidosis are discussed.
References:
1. Singh M, Mahmood M. Melioidosis: the great mimicker. J Community Hosp Intern Med Perspect. 2017;7(4):245-247. doi:10.1080/20009666.2017.1348875.
2. White N J. Melioidosis. Lancet. 2003;361(9370):1715-22. doi: 10.1016/s0140-6736(03)13374-0.
3. Cheng AC, Currie BJ. Melioidosis: Epidemiology, pathophysiology, and management. Clin Microbiol Rev. 2005;18(2):383–416. doi: 10.1128/CMR.18.2.383–416.2005.
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Authors
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Dr Marco Chan -